NeoStrata ® Product Range

The NeoStrata Legacy

The creators of NeoStrata Company, Inc., Drs. Eugene Van Scott and Ruey Yu are internationally recognized for making the ground breaking discovery that Alpha Hydroxy Acids (AHAs) have profound beneficial effects on human skin.

Drs. Eugene Van Scott and Ruey Yu are co-inventors, with more than 100 U.S. and foreign patents and are authors of numerous journal articles. They wrote the chapter in the definitive textbook for the field of cosmetic dermatology, “Alpha Hydroxy Acids, PolyHydroxy Acids, Lactobionic Acids and Their Topical Application” in the Textbook of Cosmetic Dermatology.

NeoStrata Range

From oily skin, large pores and acne, to mottled pigmentation, dark spots, dark circles and visible signs of ageing, NeoStrata has product categories to address specific patient needs.  The patient condition checklist below will help identify which NeoStrata category best suits your patient.

NeoStrata cosmeceutical skincare is formulated carefully to meet needs of both physicians and patients in terms of providing clearly visible results and ease of use. It provides 6 clear pathways facilitating product selection and regimen development according to specific skin needs.

Skin Active – advanced antiageing for mature skin.

Resurface – to improve skin texture and clarity.

Restore – antiageing for sensitive skin.

Refine – antiageing for oily/blemished skin.

Targeted treatment: for specific skin needs, eg sun protection, spot treatment, severe dry skin.

Enlighten – for pigmented skin.

Clinical Research and Published Works


Journal of Drugs and Dermatology publications

Schlessinger J, Green BA, Edison BL, Murphy L, Sabherwal Y. A firming neck cream containing N-acetyl glucosamine significantly improves signs of aging on the challenging neck and décolletage. J Drugs Dermatol 2016;15(1):47-52.

Farris PK, Edison BL, Weinkauf RL, Green BA. A novel, volumizing cosmetic formulation significantly improves the appearance of target glabellar lines, nasolabial folds and crow’s feet in a double-blind, vehicle-controlled clinical trial. J Drugs Dermatol 2014;13(1):41-46.

Farris PK, Edison BL, Brouda I, Weinkauf RL, Green BA. A high-potency, multimechanism skin care regimen provides significant antiaging effects: Results from a double-blind, vehicle-controlled clinical trial. J Drugs Dermatol 2012:11(12)1447-1454.

Akamine KL, Gustafson CJ, Yentzer BA, Edison BL, Green BA, Davis SA, Feldman SR. A double-blind, randomized clinical trial of 20% alpha/poly hydroxy acid cream to reduce scaling of lesions associated with moderate, chronic plaque psoriasis. J Drugs Dermatol 2013; 12(8):855-859.

Bagel J. LCD plus NB-UVB reduces time to improvement of psoriasis vs. NB-UVB alone. J Drugs Dermatol 2009;8(4):351-357.

Cosmetic Dermatology publications

Green BA, Edison BL, Sigler ML. Antiaging effects of topical lactobionic acid: results of a controlled usage study. Cosmetic Dermatology 2008;21(2):76-82.

Green BA., Edison BL, Wildnauer RH, Sigler ML. Lactobionic acid and gluconolactone: PHAs for photoaged skin. Cosmetic Dermatology 2001;14(9):24-28.

Journal of Cosmetic Dermatology publications

Johnson C, Edison BL, Brouda I, Green BA. A novel LCD (coal tar) solution for psoriasis does not discolor naturally light or color-processed hair in an exaggerated exposure test model. J Cosmet Dermatol 2009;8:211-215.

Draelos ZD, Green BA, Edison BL. An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients. J Cosmet Dermatol 2006;5:23-29.

Green B. After 30 years…the future of hydroxyacids. J Cosmet Dermatol 2005;4:44-45.

Cutis publications

Effron C, Briden ME, Green BA. Enhancing cosmetic outcomes by combining superficial glycolic acid (AHA) peels with nonablative lasers, intense pulsed light, and trichloroacetic acid peels. Cutis 2007;79(suppl 1):4-8.

Edison BL, Green BA, Wildnauer RH, Sigler ML. A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen. Cutis 2004;73(suppl 2):14-17.

Grimes PE, Green BA, Wildnauer RH, Edison BL. The use of polyhydroxy acids (PHAs) in photoaged skin. Cutis2004;73(suppl 2):3-13.

Clinics in Dermatology publication

Green BA, Yu RJ, Van Scott EJ. Clinical and cosmeceutical uses of hydroxyacids. Clinics in Dermatol 2009;27:495-501.

British Journal of Dermatology publication

Berardesca E, Distante F, Vignoli GP, Oresajo J, Green B. Alpha hydroxyacids modulate stratum corneum barrier function. British Journal of Dermatology 1997;137:934-938.

Various Journal Publications

Green BA, Weinkauf RL. Powerful peptides. Body Language 2011; 13(6): 41.

Green BA. Hydroxyacids for anti-ageing skincare. Body Language 2011; 13(4): 50-51.

Green BA. Breakthroughs in peel technology. Healthy Aging 2006;1(5):80.

Green BA. What every esthetician should know about dry skin. Skin Inc. 2003;15(2):75-81.

Kraechter HU, McCaulley JA, Edison BL, Green BA, Milora DJ. Amphoteric hydroxy complexes: AHAs with reduced stinging and irritation. Cosmetics & Toiletries 2001;116(1):47-52.

Bernstein EF, Green BA, Edison B, Wildnauer RH. Poly hydroxy acids (PHAs): clinical uses for the next generation of hydroxy acids. Skin & Aging 2001;9(Suppl):4-11.

Green BA. Lactobionic acid. Skin Inc 2000;11:62-65.

Book Chapters

Green BA, Van Scott EJ, Yu RJ. Clinical uses of hydroxyacids. In: Draelos ZD ed. Cosmetic Dermatology: Products and Procedures, 2nd ed. West Sussex, UK: Wiley-Blackwell; 2016:346-356.

Green BA, Sabherwal Y. Antiaging benefit ingredients: AHAs, PHAs, and bionic acids. In: Draelos ZD, Dover J, Alam M, eds. Procedures in Cosmetic Dermatology: Cosmeceuticals, 3rd ed. London: Elsevier; 2016:99-116.

Green BA. Cosmeceutical Uses and Benefits of Alpha, Poly and Bionic Hydroxy Acids. In: Farris PK. ed. Cosmeceuticals and Cosmetic Practice. West Sussex, UK: Wiley-Blackwell; 2014:69-80.

Small R, Green B. Skin care products. In: Usatine et al, eds. Dermatologic and Cosmetic Procedures in Office Practice. Philadelphia, PA: Elsevier Saunders; 2012:286-297.

Green BA, Van Scott EJ, Yu RJ. Clinical uses of hydroxyacids. In: Draelos ZD ed. Cosmetic Dermatology: Products and Procedures, 1st ed. West Sussex, UK: Wiley-Blackwell 2010; 327-334.

Green BA, Briden ME. PHAs and bionic acids: next generation hydroxy acids. In: Draelos Z, Dover J, Alam M, eds. Procedures in Cosmetic Dermatology: Cosmeceuticals, 2nd edn. Philadelphia, PA: Saunders Elsevier; 2009:209-215.

Briden ME, Green BA. Topical exfoliation – clinical effects and formulating considerations. In: Draelos ZD, Thaman LA,eds. Cosmetic Formulations of Skin Care Products. New York, NY: Taylor & Francis Group; 2006:237-250.

Briden ME, Green BA. The next generation hydroxyacids. In: Draelos Z, Dover J, Alam M, eds. Procedures in Cosmetic Dermatology: Cosmeceuticals. Philadelphia, PA: Elsevier Saunders;2005:205-212.

Neoretin ® Product Range

The Neoretin Brand

Neoretin ® is an antiaging and depigmenting cosmetic line based on the exclusive and innovative RetinSphere ®, technology which gives the skin the efficacy and benefits of retinoic acid, such as exfoliation and epidermal renewal, without the negative effects, such as irritation and inflammation.

Neoretin ® is devised for the comprehensive care of skin types with pigmentation problems and tendency of liver spots, and those with signs of photoaging. As well as effective depigmenting action given by a complex of six agents that act in all the phases of melanin production.

Retinsphere ®

Retinsphere ® is the base active ingredient of our depigmentation cosmetic line Neoretin ®.

It is an innovative combination of retinoids that stimulates epidermal renewal and boosts penetration of the active ingredients. Skin is smooth and favours uniform tone.

After testing on Asian and Caucasian subjects, tolerability was extremely good without the typical adverse effects of retinoids, such as irritation and inflammation.

Composition of Retinsphere ®

Retinsphere ® is constituted by an innovative combination of two retinoids at suitable concentrations for cosmetic use.

Hydroxypinacolone Retinoate: This compound derived from retinoic acid has been modified to reduce its acidity and thus avoid skin irritation.

Retinol Glycospheres: Retinol or Vitamin A is a more unstable molecule than retinoic acid but with similar results and without side effects.  RetinSphere glycospheres manages to keep the retinol molecule stable for longer, protect it from external agents that can oxidate it and facilitate its penetration to the deepest layers of the epidermis.

How does Retinsphere Technology ® work?

  • It favours cell growth and differentiation to combat wrinkles, liver spots and fine lines.
  • It acts on Tyrosinase formation, the enzyme responsible for melanin production to reduce the appearance of liver spots.
  • It normalises follicular epithelium formation so that it is not obstructed and result in acne.

Clinical Research

SM Journal of Dermatology

Safety and Efficacy of a New Regimen in Homogenizing and Brightening Skin Complexion

Journal of Dermatology and Clinical Research
Dermaceutic Product Range

Dermaceutic Laboratoire

Dermaceutic Laboratoire is the partner of choice for over 30,000 aesthetic dermatology specialists throughout the world.

One of the first cosmeceutical companies to develop products using ingredients such as hyaluronic acid, stabilized vitamin C, and glycolic acid; Dermaceutic has led the cosmeceutical industry in the discovery of effective combinations of ingredients for use in aesthetic dermatology.

Through a progressive approach with peel intensity adapted to each patient, and a personal homecare regimen, optimal results can be achieved.

The efficacy of Dermaceutic’s cosmeceutical and peel treatment protocols is supported by extensive clinical trials, and the company’s collaboration with industryleading practitioners from around the globe.

The Dermaceutic homecare range focuses on the three essential areas of skin rejuvenation: stimulation, protection and repair. It was created to address most skin types’ needs- from pigmentation to fine lines to acne- and contains a unique combination of active ingredients at unequalled concentrations for a luminous complexion and firmer, smoother skin. The products are packaged in airless bottles to ensure optimum hygiene, ease of use and a minimal concentration of preservatives.

Dermaceutic has a deep knowledge of the most efficient chemical peel agents and has thus also developed a range ofpeelings used by skincare specialists worldwide. With Dermaceutic professional products, the skincare specialist is able to treat general skin concerns; from the superficial and harmless, to the most complex and delicate cases. Chemical peels can be defined as an accelerated form of exfoliation, induced by a chemical agent. It activates different types of modifications in the skin, depending on the depth of the peel.

Professional Peels:

Skin specialists will advise on the most suitable peel, depending on the treatment objective. The different peel strengths are:

Gentle peels (Mask Peel and Milk Peel)

Suitable for treating: dull complexion, first signs of ageing, greasy, acne-prone skin, visible pores, excess sebum, wrinkles, epidermal stimulation.

De-pigmentation peels (Mela Peel and Mela Cream)

Suitable for treating: pigmentation spots, pregnancy dark spots, melasma, post-inflammatory pigmentation.

Rejuvenation peels (Cosmo Peel and Cosmo Cream)

Suitable for treating: ageing skin, smoker’s complexion,dark spots, wrinkles, stretch marks.

Heliocare Product Range


Heliocare is a simple, one-a-day dietary supplement made with Fernblock® Polypodium leucotomos extract (PLE).

This natural extract is packed with antioxidant properties that help maintain your skin’s ability to protect itself against the aging effects of free radicals.*

What is Heliocare?

Powerful, unique, and clinically proven antioxidant properties — all in a single capsule
What if you could add a one-a-day dietary supplement to your morning routine and help your skin protect itself from the harmful effects of free radicals? With Heliocare’s powerful antioxidant formula, you can. Fernblock® PLE Technology harnesses the power of the unique Polypodium leucotomos fern, helping your skin protect itself and maintain its resilience and youthful appearance.*

How It Works

Heliocare’s exclusive, clinically proven ingredient is derived from nature itself — the fascinating Polypodium leucotomos fern, found in the wilds of Central and South America. Once an aquatic plant, this fern adapted to life on land and created its own protection from the harsh effects of free radicals in the environment.

The antioxidants in the Polypodium leucotomos extract (PLE) help protect against the aging effects of free radicals. Similarly, Heliocare helps your skin protect itself and maintain its youthful look.*

Heliocare is a one-a-day dietary supplement. 365 days of helping your skin protect itself. Heliocare affects the skin over your entire body and won’t be washed away by swimming, sweating and other activities.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

(PLE) is an acronym for Polypodim Leucotomos Extract. The powerful antioxidant formula in each HELIOCARE® capsule was developed by leading dermatology experts and is naturally derived from Polypodium leuctomos (Calaguala), a fern native to Central and South America that has been used for centuries as a remedy for skin-related conditions. HELIOCARE® harnesses these natural antioxidants to reduce harmful free radicals.*

Clinical Research

Journal of the American Academy of Dermatology

Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin

Orally administered polypodium leucotomos extract decreases psoralen-UVA–induced phototoxicity, pigmentation, and damage of human skin

Sandton Aesthetic Institute Product Range

SAI Skin Care

Formulated by world-renowed Dr Alastair Clark in South Africa, each product within the SAI range & their active ingredients are carefully selected & constructed to offer not only the most incredible results but the highest quality standards too.

SAI Product Range

Hydrating Day Cream

The daily staple of any homecare range is a potent & active day cream. We want to give your skin a velvety finish by offering superb & lasting hydration to your skin.

A key ingredient within the SAI Hydrating Day Repair Cream is Pro-Vitamin B5. This is a genius ingredient that offers a multitude of benefits:

  • It is a deeply hydrating moisturiser
  • It acts as an anti-inflammatory – this immobilises inflammation damage caused by sun exposure or lifestyle choices (including stress).

The SAI Hydrating Day Repair Cream absorbs incredibly quickly so as not to slow your morning skin regime down, and it will leave your skin velvety smooth. The entire SAI range of products is available online, featuring alongside a number of other household names.

SAI Rich Night Repair Cream

Perfect for application during rest, our SAI Night Repair cream will improve & repair skin barrier function to enhance not only aesthetic results but also repair your skin after the daily rigours of daily living.

SAI AHA Cleanser

This offers patients cleansing to suit their skin & chemical exfoliation to ensure a bright daily complexion.

SAI Glyco-Lactic Cleanser Intense

This is a beefed up version of our Glycol-Lactic Creamy Cleanser and used to combat dry skin from the very first use. It is just perfect to help correct your skin barrier layer going into summer after a cold biting winter.

SAI Alpha/Beta Cleanser

A slightly more aggressive cleanser derived of only the highest purity AHA/BHA acids. This cleanser will be available for very specific skin types and will be highly beneficial to those on ongoing anti-ageing aesthetic treatments for enhanced & prolonged results.
SAI Sunblock SPF 50

Without daily & reapplication of a broad-spectrum sunblock many of our homecare efforts will be in vain. This is a gentle sunblock suitable for all skin types that will protect your skin from sun damage that is primary cause of wrinkle formation & visible age.